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Polley, Eric
One or more keywords matched the following properties of Polley, Eric
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keywords Data Science
overview Director, Biostatistics Laboratory Eric Polley, PhD is an Associate Professor in the Department of Public Health Sciences at The University of Chicago where he is the faculty director for the Data Science concentration in the Master of Public Health program. Dr. Polley was previously an Assistant Professor of Biostatistics in the Department of Quantitative Health Sciences at Mayo Clinic (2015-2021) and a mathematical statistician in the Biometric Research Branch at the U.S. National Cancer Institute (2012-2015). Dr. Polley received his PhD in biostatistics from the University of California, Berkeley in 2010. With Mark van der Laan, they developed the Super Learner ensemble prediction methodology. His research area involves the development and evaluation of prediction methods, innovative methods for diagnostic and prognostic prediction, and precision medicine clinical trial design.
One or more keywords matched the following items that are connected to Polley, Eric
Item TypeName
Concept Urinary Bladder
Concept Alleles
Concept Computer Simulation
Concept Base Sequence
Concept Emergency Service, Hospital
Concept Carcinoma, Non-Small-Cell Lung
Concept Mass Screening
Concept Length of Stay
Concept Heat-Shock Proteins
Concept Neoplasm Staging
Concept Neoplastic Syndromes, Hereditary
Concept Reference Standards
Concept Skilled Nursing Facilities
Concept Cohort Studies
Concept Sebaceous Glands
Concept Sensitivity and Specificity
Concept Sulfonylurea Compounds
Concept Skin
Concept Staphylococcal Infections
Concept Software
Concept Genome
Concept Ultrasonography
Concept United States
Concept Genes, BRCA2
Concept Trimethoprim, Sulfamethoxazole Drug Combination
Concept Supine Position
Concept Case-Control Studies
Concept Sequence Analysis, DNA
Concept Protein Structure, Tertiary
Concept HSP70 Heat-Shock Proteins
Concept Neoplasms, Squamous Cell
Concept Oxidative Stress
Concept Muscle, Skeletal
Concept Reactive Oxygen Species
Concept Genetic Association Studies
Concept Exome
Concept Biological Specimen Banks
Concept Sarcoma, Alveolar Soft Part
Concept Oligonucleotide Array Sequence Analysis
Concept Genes, BRCA1
Concept Spinocerebellar Ataxias
Concept National Cancer Institute (U.S.)
Concept HSP27 Heat-Shock Proteins
Concept Sarcoma
Concept Staphylococcus
Concept Structure-Activity Relationship
Concept Sulfonamides
Concept Ubiquitin-Protein Ligases
Concept TOR Serine-Threonine Kinases
Concept High-Throughput Nucleotide Sequencing
Concept Models, Statistical
Concept Small Cell Lung Carcinoma
Concept Survival Analysis
Concept Survival Rate
Concept Patient Selection
Concept Cellular Senescence
Concept Small Molecule Libraries
Concept Stroke
Concept Statistics, Nonparametric
Concept HSP90 Heat-Shock Proteins
Concept Tumor Suppressor Proteins
Concept Genome-Wide Association Study
Concept Amyloid Precursor Protein Secretases
Concept Metagenome
Concept Data Interpretation, Statistical
Concept Drug Administration Schedule
Concept Drug Screening Assays, Antitumor
Concept Follow-Up Studies
Concept Longitudinal Studies
Concept Prospective Studies
Concept Retrospective Studies
Concept Speech
Concept User-Computer Interface
Concept Signal Transduction
Concept Tumor Suppressor Protein p53
Concept Ultrasonography, Mammary
Concept Sequence Analysis, RNA
Concept Receptors, Somatomedin
Concept Disease-Free Survival
Concept Polymorphism, Single Nucleotide
Concept Quantitative Trait Loci
Concept Genetic Loci
Academic Article Two-stage adaptive cutoff design for building and validating a prognostic biomarker signature.
Academic Article A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers.
Academic Article Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer.
Academic Article Small Cell Lung Cancer Screen of Oncology Drugs, Investigational Agents, and Gene and microRNA Expression.
Academic Article New insights on PI3K/AKT pathway alterations and clinical outcomes in breast cancer.
Academic Article Free HIV antiretroviral therapy enhances adherence among individuals on stable treatment: implications for potential shortfalls in free antiretroviral therapy.
Academic Article Automatic Deep Learning Semantic Segmentation of Ultrasound Thyroid Cineclips Using Recurrent Fully Convolutional Networks.
Academic Article Association between clot composition and stroke origin in mechanical thrombectomy patients: analysis of the Stroke Thromboembolism Registry of Imaging and Pathology.
Academic Article A Population-Based Study of Genes Previously Implicated in Breast Cancer.
Academic Article Does Body Position Affect Ultrasound Measurements of Bladder-Wall Elasticity?
Academic Article Characterizing thrombus with multiple red blood cell compositions by optical coherence tomography attenuation coefficient.
Academic Article Individualized-thresholding Shear Wave Elastography combined with clinical factors improves specificity in discriminating breast masses.
Academic Article Effect of Germline Mutations in Homologous Recombination Repair Genes on Overall Survival of Patients with Pancreatic Adenocarcinoma.
Academic Article Contribution of Inherited DNA-Repair Gene Mutations to Hormone-Sensitive and Castrate-Resistant Metastatic Prostate Cancer and Implications for Clinical Outcome.
Academic Article Mutation prevalence tables for hereditary cancer derived from multigene panel testing.
Academic Article Evaluation of Germline Genetic Testing Criteria in a Hospital-Based Series of Women With Breast Cancer.
Academic Article Super Learner for Survival Data Prediction.
Academic Article The Contribution of Germline Predisposition Gene Mutations to Clinical Subtypes of Invasive Breast Cancer From a Clinical Genetic Testing Cohort.
Academic Article A clinical guide to hereditary cancer panel testing: evaluation of gene-specific cancer associations and sensitivity of genetic testing criteria in a cohort of 165,000 high-risk patients.
Academic Article Interaction between the microbiome and TP53 in human lung cancer.
Academic Article Triple-Negative Breast Cancer Risk Genes Identified by Multigene Hereditary Cancer Panel Testing.
Academic Article Risk of Different Cancers Among First-degree Relatives of Pancreatic Cancer Patients: Influence of Probands' Susceptibility Gene Mutation Status.
Academic Article Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer.
Academic Article Emollient use alters skin barrier and microbes in infants at risk for developing atopic dermatitis.
Academic Article Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells.
Academic Article RefCNV: Identification of Gene-Based Copy Number Variants Using Whole Exome Sequencing.
Academic Article Analytical Validation and Application of a Targeted Next-Generation Sequencing Mutation-Detection Assay for Use in Treatment Assignment in the NCI-MPACT Trial.
Academic Article Clinical trials for precision oncology using next-generation sequencing.
Academic Article Systemic treatment and radiotherapy, breast cancer subtypes, and survival after long-term clinical follow-up.
Academic Article Cediranib for metastatic alveolar soft part sarcoma.
Academic Article Shifts in human skin and nares microbiota of healthy children and adults.
Academic Article Cancer susceptibility gene mutations in type I and II endometrial cancer.
Academic Article Characterizing Potentially Preventable Admissions: A Mixed Methods Study of Rates, Associated Factors, Outcomes, and Physician Decision-Making.
Academic Article Frequency of mutations in a large series of clinically ascertained ovarian cancer cases tested on multi-gene panels compared to reference controls.
Academic Article Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA Expression.
Academic Article AMP kinase-related kinase NUAK2 affects tumor growth, migration, and clinical outcome of human melanoma.
Academic Article Strong functional data for pathogenicity or neutrality classify BRCA2 DNA-binding-domain variants of uncertain significance.
Academic Article Two-stage deep learning model for fully automated pancreas segmentation on computed tomography: Comparison with intra-reader and inter-reader reliability at full and reduced radiation dose on an external dataset.
Academic Article Racial and Ethnic Differences in Multigene Hereditary Cancer Panel Test Results for Women With Breast Cancer.
Academic Article Contribution of Germline Predisposition Gene Mutations to Breast Cancer Risk in African American Women.
Academic Article Combined Associations of a Polygenic Risk Score and Classical Risk Factors With Breast Cancer Risk.
Academic Article Predictive value of comb-push ultrasound shear elastography for the differentiation of reactive and metastatic axillary lymph nodes: A preliminary investigation.
Academic Article Assessment of MRI-detected lesions on screening tomosynthesis in patients with newly diagnosed breast cancer.
Academic Article HIV elite control is associated with reduced TRAILshort expression.
Academic Article Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk.
Academic Article Gene expression differences between matched pairs of ovarian cancer patient tumors and patient-derived xenografts.
Academic Article Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.
Academic Article Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models.
Academic Article Multigene Hereditary Cancer Panels Reveal High-Risk Pancreatic Cancer Susceptibility Genes.
Academic Article The National Cancer Institute ALMANAC: A Comprehensive Screening Resource for the Detection of Anticancer Drug Pairs with Enhanced Therapeutic Activity.
Academic Article Analytical Validation of the Next-Generation Sequencing Assay for a Nationwide Signal-Finding Clinical Trial: Molecular Analysis for Therapy Choice Clinical Trial.
Academic Article Diverse Human Skin Fungal Communities in Children Converge in Adulthood.
Academic Article Plasmid-Based Materials as Multiplex Quality Controls and Calibrators for Clinical Next-Generation Sequencing Assays.
Academic Article Comprehensive characterization of the Published Kinase Inhibitor Set.
Academic Article Phase I study of the heat shock protein 90 (Hsp90) inhibitor onalespib (AT13387) administered on a daily for 2 consecutive days per week dosing schedule in patients with advanced solid tumors.
Academic Article GeneMed: An Informatics Hub for the Coordination of Next-Generation Sequencing Studies that Support Precision Oncology Clinical Trials.
Academic Article Application of molecular profiling in clinical trials for advanced metastatic cancers.
Academic Article Super learning: an application to the prediction of HIV-1 drug resistance.
Academic Article Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis.
Academic Article Super learner.
Academic Article The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel.
Academic Article Testing the Relative Performance of Data Adaptive Prediction Algorithms: A Generalized Test of Conditional Risk Differences.
Academic Article Random forests for genetic association studies.
Academic Article OpenGeneMed: a portable, flexible and customizable informatics hub for the coordination of next-generation sequencing studies in support of precision medicine trials.
Academic Article Clinical Activity of the ?-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis).
Academic Article Classification of variants of uncertain significance in BRCA1 and BRCA2 using personal and family history of cancer from individuals in a large hereditary cancer multigene panel testing cohort.
Academic Article Association of ?H2AX at Diagnosis with Chemotherapy Outcome in Patients with Breast Cancer.
Academic Article Bromodomain and hedgehog pathway targets in small cell lung cancer.
Academic Article The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology.
Award or Honor Receipt NCI Director's award for the development of the NCI-MATCH clinical trial
Academic Article Exploring large weight deletion and the ability to balance confounders when using inverse probability of treatment weighting in the presence of rare treatment decisions.
Academic Article Early assessment of shear wave elastography parameters foresees the response to neoadjuvant chemotherapy in patients with invasive breast cancer.
Academic Article Differential Contribution of ASPECTS Regions to Clinical Outcome after Thrombectomy for Acute Ischemic Stroke.
Academic Article Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers.
Academic Article Prediction of Invasive Breast Cancer Using Mass Characteristic Frequency and Elasticity in Correlation with Prognostic Histologic Features and Immunohistochemical Biomarkers.
Academic Article Adipose tissue macrophage populations and inflammation are associated with systemic inflammation and insulin resistance in obesity.
Academic Article Comparison of the Prevalence of Pathogenic Variants in Cancer Susceptibility Genes in Black Women and Non-Hispanic White Women With Breast Cancer in the United States.
Academic Article Preserved skeletal muscle oxidative capacity in older adults despite decreased cardiorespiratory fitness with ageing.
Academic Article Risk of Breast Cancer Among Carriers of Pathogenic Variants in Breast Cancer Predisposition Genes Varies by Polygenic Risk Score.
Academic Article A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech.
Academic Article Risk of Late-Onset Breast Cancer in Genetically Predisposed Women.
Academic Article Quantitative Biomarkers for Cancer Detection Using Contrast-Free Ultrasound High-Definition Microvessel Imaging: Fractal Dimension, Murray's Deviation, Bifurcation Angle & Spatial Vascularity Pattern.
Academic Article Real-world Cardiovascular Outcomes Associated With Degarelix vs Leuprolide for Prostate Cancer Treatment.
Academic Article Germline Pathogenic Variants in Cancer Predisposition Genes Among Women With Invasive Lobular Carcinoma of the Breast.
Academic Article Alterations of human skin microbiome and expansion of antimicrobial resistance after systemic antibiotics.
Academic Article Breast Cancer Screening Strategies for Women With ATM, CHEK2, and PALB2 Pathogenic Variants: A Comparative Modeling Analysis.
Academic Article Ultrasound high-definition microvasculature imaging with novel quantitative biomarkers improves breast cancer detection accuracy.
Academic Article An integrative model for the comprehensive classification of BRCA1 and BRCA2 variants of uncertain clinical significance.
Academic Article Classification of BRCA2 Variants of Uncertain Significance (VUS) Using an ACMG/AMP Model Incorporating a Homology-Directed Repair (HDR) Functional Assay.
Academic Article Dismissal disagreement and discharge delays: Associations of patient-clinician plan of care agreement with discharge outcomes.
Academic Article Emulating the GRADE trial using real world data: retrospective comparative effectiveness study.
Academic Article Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival.
Academic Article Identifying treatment heterogeneity in atrial fibrillation using a novel causal machine learning method.
Concept Sitagliptin Phosphate
Concept Breast Carcinoma In Situ
Concept Smokers
Concept Symptom Assessment
Concept Response Evaluation Criteria in Solid Tumors
Academic Article Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival.
Academic Article Clot composition and recanalization outcomes in mechanical thrombectomy.
Academic Article Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C.
Academic Article Intermuscular Coherence in Spinocerebellar Ataxias 3 and 6: a Preliminary Study.
Academic Article Targeted Investigational Oncology Agents in the NCI-60: A Phenotypic Systems-based Resource.
Academic Article Comparative effectiveness of second line glucose lowering drug treatments using real world data: emulation of a target trial.
Academic Article Assessing the use of observational methods and real-world data to emulate ongoing randomized controlled trials.
Academic Article Electronic Health Records (EHRs) Can Identify Patients at High Risk of Fracture but Require Substantial Race Adjustments to Currently Available Fracture Risk Calculators.
Academic Article Signal processing and machine learning with transdermal alcohol concentration to predict natural environment alcohol consumption.
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